Ligand-regulated oligomerization of b2-adrenoceptors in a model lipid bilayer
نویسندگان
چکیده
Juan José Fung, Xavier Deupi, Leonardo Pardo, Xiao Jie Yao, Gisselle A Velez-Ruiz, Brian T DeVree, Roger K Sunahara and Brian K Kobilka* Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA, Laboratori de Medicina Computacional, Unitat de Bioestadı́stica, Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA
منابع مشابه
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
The beta(2)-adrenoceptor (beta(2)AR) was one of the first Family A G protein-coupled receptors (GPCRs) shown to form oligomers in cellular membranes, yet we still know little about the number and arrangement of protomers in oligomers, the influence of ligands on the organization or stability of oligomers, or the requirement for other proteins to promote oligomerization. We used fluorescence res...
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